Supergirl and Clark team up to stop a new threat emerging in National City; Alex feels left out while Kara’s family stays in town; a pod comes crashing down to earth. Supergirl is hurt by a kryptonite-powered villain sent by Cadmus to attack National City. Superman blames Hank since the kryptonite was stolen from the DEO. In the meantime, Kara’s first day at her new job doesn’t go as planned when she meets her new boss.